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Comprehensive assessment of oxidative stress degrees and anti-oxidant potential in dialysis patients
https://doi.org/10.50850/00000331
https://doi.org/10.50850/0000033171647787-4aa9-473a-8f40-3c50514db2e3
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本文 (1.7 MB)
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DS2_abstract.pdf (351 KB)
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DS2_Result .pdf (123 KB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||||||
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| 公開日 | 2021-03-02 | |||||||||
| タイトル | ||||||||||
| タイトル | Comprehensive assessment of oxidative stress degrees and anti-oxidant potential in dialysis patients | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | d-ROMs | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | BAP | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Dialysis treatment | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Oxidative stress | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Anti-oxidant potential | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||||
| 資源タイプ | doctoral thesis | |||||||||
| ID登録 | ||||||||||
| ID登録 | 10.50850/00000331 | |||||||||
| ID登録タイプ | JaLC | |||||||||
| アクセス権 | ||||||||||
| アクセス権 | open access | |||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
| 著者 |
Miyagawa, Akemi
× Miyagawa, Akemi
× Tateishi, Kinya
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| 公開者 | ||||||||||
| 出版者 | The Society of Analytical Bio-Science | |||||||||
| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | When the kidney is compromised, oxidative stress is aggravated by an increased rate of reactive oxygen species generation and a decreased rate of substance elimination. In addition, dialysis treatment itself is reported to be associated with oxidative stress in patients with terminal renal insufficiency. This study was conducted to determine the optimum dialysis treatment. Diacronreactive oxygen metabolite and biological anti-oxidant potential tests were performed to assess oxidative stress levels. Increased oxidative stress and decreased anti-oxidant potential were found immediately after dialysis. A comparison of dialysis membranes revealed that ABH®-PA membranes exhibited a significantly lower rate of decrease in anti-oxidant potential in terms of oxidative stress compared with Maxiflux® membranes. Analysis of biochemical parameters identified significant strong positive correlations between diacron-reactive oxygen metabolites test results and serum total protein, serum albumin, total cholesterol, high-density lipoprotein-cholesterol, and low-density lipoprotein-cholesterol for the percentage decrease and between biological anti-oxidant potential test results and inorganic phosphorus for pre-dialysis measurements. ABH®-PA should be used as the dialysis membrane to minimize the increase in the degree of oxidative stress caused by dialysis treatment. We recommend measuring serum total protein, serum albumin, total cholesterol, and inorganic phosphorus before and after dialysis sessions to better understand oxidative stress degrees and anti-oxidant potential. |
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| 学位名 | ||||||||||
| 学位名 | 博士（臨床検査学） | |||||||||
| item_10006_degree_grantor_9 | ||||||||||
| 学位授与機関識別子Scheme | kakenhi | |||||||||
| 学位授与機関識別子 | 26201 | |||||||||
| 学位授与機関名 | 香川県立保健医療大学 | |||||||||
| 学位授与年度 | ||||||||||
| 2020 | ||||||||||
| 学位授与年月日 | ||||||||||
| 学位授与年月日 | 2020-09-16 | |||||||||
| dissertation_number | ||||||||||
| 学位授与番号 | 甲第2号 | |||||||||
| 権利 | ||||||||||
| 権利情報 | open access | |||||||||
| 情報源 | ||||||||||
| 関連名称 | https://kagawa-puhs.repo.nii.ac.jp/?action=pages_view_main&active_action=repository_view_main_item_detail&item_id=337&item_no=1&page_id=13&block_id=21 | |||||||||
| フォーマット | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | application/pdf | |||||||||
| 出版タイプ | ||||||||||
| 出版タイプ | VoR | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
| 日本十進分類法 | ||||||||||
| 主題Scheme | NDC | |||||||||
| 主題 | 491.4 | |||||||||
| bibliographic_information |
en : International Journal of Analytical Bio-Science 巻 8, 号 4, p. 83-92, 発行日 2020-12-31 |
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| item_10006_publisher_28 | ||||||||||
| 出版者 | The Society of Analytical Bio-Science | |||||||||
| item_10006_source_id_23 | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 21877912 | |||||||||
| item_10006_relation_26 | ||||||||||
| 識別子タイプ | NAID | |||||||||
| 関連識別子 | 40022452841 | |||||||||
| item_10006_link_29 | ||||||||||
| International Journal of Analytical Bio-Science 8(4)83-92 | ||||||||||
| http://plaza.umin.ac.jp/~e-jabs/8/8.83.pdf | ||||||||||
| item_10006_description_30 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | Thesis or Dissertation | |||||||||
